Marijuana (THC) |
Marijuana (THC) is a mood altering drug
derived from the flowering portion of the hemp plant. Smoking is the primary method of
use. Marijuana contains a number of active ingredients collectively known as cannabinoids.
The primary cannabinoid in marijuana is THC. Marijuana use affects motor skills, eye
tracking, and perceptual functions, but no consistent correlation has been established
between the degree of use and the onset of physical effects.1 |
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Studies have shown that passive inhalation of marijuana smoke under
restrictive conditions of extreme exposure can result in the presence of detectable
(greater than 20 ng/mL but less than 100 ng/mL) levels of marijuana metabolites in the
urine of exposed individuals.1 It has been found, however, that when a 50 ng/mL
screening level is chosen, passive inhalation may be ruled out at the 95% confidence
limit.1,2 |
Cocaine |
Cocaine is a central nervous system stimulant
producing an intense feeling of euphoria. Although tolerance to and physical dependence on
cocaine have not been demonstrated, psychological dependence probably develops.3 The two most prevalent methods of using cocaine are nasal inhalation (snorting) and
smoking of the free-base form of the drug (crack).4 |
Opiates |
Opiates are a class of natural and
semi-synthetic drugs that include morphine, codeine and heroin. Opiates affect the central
nervous system and produce feelings of euphoria. Abusers of opiates develop both a
physical and psychological dependence on the drugs. Codeine and morphine are powerful
analgesics used in prescription drugs. Heroin, a derivative of morphine, is truly an
abused drug. Heroin can be taken several ways: smoking, nasal inhalation (snorting),
subcutaneous injections (skin popping) and intravenous injections (mainlining).5 |
Amphetamines |
Amphetamines are mind-altering stimulants
that excite the central nervous system. This group of compounds includes amphetamine, methamphetamine and related designer drugs that are similar both
chemically and pharmacologically to the naturally occurring compounds, epinephrine and
norepinephrine. Amphetamines produce a wakeful state accompanied by a sense of increased
energy, self-confidence, well-being and even euphoria. Prolonged and/or high dose use of
amphetamines can result in irrational behavior, poor mental acuity and paranoid behavior
including psychosis.6
Amphetamines are usually taken orally, intravenously or by nasal
inhalation (snorting). |
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PCP |
PCP is a hallucinogenic drug available in
powder, capsule or tablet form. It may be taken by nasal inhalation (snorting),
intravenously or orally. It may also be smoked after mixing with marijuana or other
shredded leaves such as parsley or oregano.7
The effects of PCP are dose related but vary in severity from individual
to individual. These effects vary from simple stimulation to schizophrenic psychosis. With
large doses, mood changes are totally unpredictable and irrational, violent actions may
occur. Trauma is one of the leading causes of death from PCP intoxication.8 |
1. Lifshitz, M.S. and DeCresce, R.P. What you should know about
screening for drugs of abuse. Med. Lab. Prod. 2(12):17-18. 1987.\
2. Perez-Reyes, M. Guiseppi, S., Macon, A.P., and Davis, K.H.
Passive inhalation of marijuana smoke and urinary excretion of cannabinoids. Clin.
Pharmacol. Ther. 34:36-41. 1983.
3. Gay, G.R., et al. Cocaine: History, epidemiology, human
pharmacology, and treatment. A perspective on a new debut from an old girl in Rappolt.
R.T.(ed): Clinical Toxicology. Marcel Dekker, Inc., New York. 1975
4. Bastian, B.J. The cocaine nightmare. Carolina Tips 50:21-23.
1987.
5. Hawks, R.L. and Chiang, C.N. (eds). Urine Testing for Drugs of
Abuse. NIDA Research Monograph 73. U.S. Department of Health and Human Services.
Washington, D.C. 1986. p.95.
6. Blum, K. Handbook of Abusable Drugs. Gardener Press,
Inc. New York, New York, 1984. pp. 305-349.
7. DeCresce, R.P., Lifshitz, M.S., Mazura, A.C. and Tilson, J.E. Drug
Testing in the Workplace. ASCP Press. American Society of Clinical Pathologists.
Chicago, Illinois. 1989. pp. 105-109.
8. Budd. R.D. and Lindstrom, D.M. Characteristics of Victims of
PCP - Related Deaths in Los Angeles County. J. Toxicol. Clin. Toxicol. 19:997-1004. 1983.
9. Federal Register: Volume 59:2998. June 9, 1994.